Taught by her astronomer father, Maria Mitchell was the first professional woman astronomer in the United States and became a professor of astronomy at Vassar College (1865-1888). She was the first woman member of the American Academy of Arts and Sciences (1848), and was president of the American Association for the Advancement of Science.
On October 1, 1847, she spotted a comet, for which she was given credit as the discoverer.
She was also involved in the anti-slavery movement. She refused to wear cotton because of its connection with slavery in the South, a commitment she continued after the Civil War ended. She also supported women's rights efforts and traveled in Europe.