Sarah and Angelina Grimké, sisters who grew up in a slaveholding family in the South, became Quakers, anti-slavery activists and women's rights advocate. Sarah wrote "An Epistle to the Clergy of the Southern States" in 1836, to counter typical Biblical arguments used by clergy to justify slavery on religious grounds. Angelina published her tract, "Appeal to the Christian Women of the South," the same year. The two became infamous for speaking in public, something that was still considered improper for women, especially if the audience included both men and women.

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